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Benefits of EPIFLO Over Other Therapies

Transdermal Continuous Oxygen Therapy

EPIFLO® Product Benefits and User Advantages

  • Easy to Use- No special storage conditions. Simple on/off switch. Applies to wounds in seconds.
  • Minimal Training – Simply place oxygen cannula at center of wound and all other dressings go on top sequentially.
  • Fits all anatomic wound sites – The unit itself fits into a pocket so EPIFLO® can be used wherever a dressing can be placed.
  • Patient Mobility – The patient is free to ambulate and carry on normal daily living while receiving treatment. EPIFLO® can be worn beneath clothing without impairing its operation.
  • Safe – Non-implantable,
    non ingestible, no tanks, chambers or oxygen storage.
  • Continuous treatment for extended durations-Uninterrupted sustained delivery of oxygen 24 hours a day.
  • Convenient – No daily trips to the hospital to receive oxygen treatment. Dressing changes as needed to maintain good wound care.
  • Cost effective – Reduces treatment time, thereby reducing overall cost. Lower cost per day than HBOT (Hyperbaric Oxygen Therapy) and NWPT (Negative Wound Pressure Therapy.)
  • Versatile – Compatible with outpatient, inpatient and community care environments.
  • Effective – May
    be used for a broad list of chronic wounds – Efficacy proven on most
    recalcitrant, non healing, or slow healing chronic wounds
  • Compact – Dimensions 4.8cm X 6.0cm X 2.5 cm (approx.)
       
       
    Products  

How does it work?

EPIFLO® combines a specialized process to extract oxygen from the air and deliver it to the wound via a very small cannula (tube). The oxygen flows continuously into the 152 cm (60”) long #5 Fr. cannula. 

The end of the cannula is placed onto the wound site and covered with an occlusive dressing or pressure dressing (see Instructions for Use). The dressing does not inflate and the patient has no sense of air movement. 

The oxygen delivered is at a low flow rate so the wound will not dry out. Some clinicians suggest that EPIFLO® mimics the bloodstream in delivering the necessary metabolic energy to oxygen starved cells.  EPIFLO® energizes ischemic cells to ‘jump start’ the natural healing process.

Oxygen blanketing the wound helps metabolically to encourage cells to form extracellular matrix components including collagen and brings about tissue regeneration evidenced by new granulation tissue,neo-vascularization and other facets of skin development.

Comparison of Oxygen Treatment Modalities

EPIFLO® Differentiating Advantage

“…although treatment conditions were normobaric by design, partial oxygen tension in the exposed tissues approached similar levels to tension measured in hyperbaric oxygen therapy, delivered systemically by means of blood flow.”

Said, H.K. et al. Arch Surg. 2005; 140:998-1004 [Wound Healing Research Lab, Division of Plastic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Ill.]s

 
EPIFLO®
HBO Chamber
Topical Chamber
 
 
       
Method of action transdermal continuous delivery; oxygen flows 24/7 respiratory & systemic perfusion; intermittent topical perfusion; intermittent
Daily oxygen exposure 24 hrs continuous 1.5 – 2.0 hrs 1.5 – 2.0 hrs
Hours of treatment  per week 168 hours 6 – 10 hours 6 – 10 hours
Oxygen flow rate 3 milliliters per hr 600 liters per hr 60 liters per hr
Oxygen purity 99+ % – maintains moist wound healing 99+ % dry 99+ % dry
Oxygen pressure normobaric; 1.0 atm 2.0 – 3.0 atm 1.05 atm
Local pO2 at wound site – during treatment 350 – 400 mm Hg  24 / 7
(168 hours/week)		 1520 – 2280 mm Hg 
(6 – 10 hours/week)		 798 mm Hg 
(6 – 10 hours/week)
Local pO2 at wound site under occlusive dressing – post treatment 350 – 400 mm Hg  continuous < 50 mm Hg < 50 mm Hg
Dressing changes every 2 – 7 days; PRN after each treatment after each treatment
Treatment target area wound under occlusive dressing full body entire limb
Oxygen treatment risks none observed systemic nerve damage, death temporary tissue toxicity
Treatment setting anywhere facility facility or home care
Patient mobility during treatment fully ambulatory confined to chamber stationary
System weight three ounces 1,000’s – 10,000’s lbs varies, > 10 lbs

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